Google has adopted a standard where any link with the attribute rel="nofollow" is not spidered by google.

This can effectively dampen the enthusiasm of spammers to spam your comments (comment spam).
It is like throwing the baby with the bathwater. In fact if a blogger is averse to people putting in links he can always disallow anchor tags in the comments.
And I don't think it will have significant impact on reducing comment spam. Because automated tools are used for comment spamming and there will always be certain sites which will not implement this. Also other search engines use link based ranking like Microsoft and things will not change overnight, if they change at all.
This move will only serve Google to improve its search engine ranking, nothing more.

Based on my experience I think that CAPTCHA is the best way (with numerical computation or audio alternatives for visually impaired) to stop comment spam fully.

I started receiving around 600 comment spams a day. After installing CAPTCHA the number came down to 0 (zero) and has remained ever since! Frankly I don't think a better alternative is required.

So to answer the original question - Say no to "nofollow" is my theme.