The Moscow chemists have suggested a way to produce insulin in pills instead of injections.在莫斯科化学家曾建议的方式产生胰岛素在丸而不是注射。 They have developed polymeric capsules that would protect insulin from destructive effect of digestive juices.他们开发的聚合物胶囊将保护胰岛素不受破坏性的影响，消化果汁。


To create such capsules, the researchers used two polymers - positive protamin and negative dextransulphate.创造这样的胶囊中，研究人员用了两个聚合物-p rotamin积极和消极的d extransulphate。 They formed layers in series one upon the other according to the plus towards minus principle and made a multi-layer covering around the insulin filling, which makes up to 85 percent of the entire microparticle.他们形成层在一系列一后，其他根据该加对减的原则，并提出了多层次，涵盖周围胰岛素填补，使得高达85 ％的整个微粒。

Insulin covered by protective capsule is stable at pH from 1.7 to 5 units, when pH increases higher than 5 units, insulin gets released.胰岛素所涵盖的保护胶囊是稳定的在pH值从1.7至5个单位，当pH值增加，高于5月的单位，胰岛素获得释放。 Further pH increase up to 8 units results in accelerated protein release rate.进一步增加pH值高达8单位，结果在加速蛋白质的释放速率。 Such behavior of particles occurs due to the fact that at pH higher than 5.5 insulin acquires negative charge and its bond with the negatively charged polymer of the first layer - dextransulphate – gets destroyed.这种行为的粒子发生因事实，即在pH值高于5.5胰岛素收购负电荷和债券，与带负电荷的聚合物的第一层-d extransulphate-获得销毁。

Such pH-dependence of protective polymeric capsules provides fundamental capability to create insulin in pills.如pH值的依赖，保护聚合物胶囊提供了基本的能力，创造胰岛素的药丸。 In the stomach, where medium is extremely acid, these capsules would protect the insulin molecule and would not allow its destruction.在胃，中等是极酸，这些胶囊能保护胰岛素分子不会允许其销毁。 Having gone through the stomach and having reached the small intestine and ileum, where pH reaches 6 to 8 units, capsules will start to excrete insulin intensely.经过胃和到达小肠和回肠，其中pH值达到6至8个单位，胶囊将开始分泌胰岛素激烈。 In thin intestines, insulin can penetrate blood.在薄肠，胰岛素可以穿透血。 Therefore, the capsule determines by itself where insulin should be retained in closed form and where it should be released.因此，胶囊决定本身胰岛素的地方应予以保留，在非公开的形式和它应该被释放。

And the best part is that the protective material is bio-degradable.和最好的部分是，该防护材料是可生物降解的。 This could also lead to delivery of several antibiotics and other medicines safely by oral means.这也可能导致交货几种抗生素和其他药品，口服安全的手段。

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