One-day treatment with the anticancer drug carboplatin is as一次為期一天的治療與抗癌藥物卡鉑是作為
effective and less toxic than three weeks radiation therapy for a type有效和毒性較低的超過三個星期放射治療A型
of testicular cancer, according to a report published in this week’s對睾丸癌,根據發表的一份報告在這週的
issue of問題 The Lancet柳葉刀 .

For the last 50 years standard care for stage 1 seminoma - a cancer of the testes - has been surgical removal of the cancerous testicle (hemi-castration) followed by three weeks radiotherapy.在過去的50年標準,照顧第1階段精-癌症的睾丸-已手術切除癌睾丸(半閹割),其次是三週放射治療。 However, patients treated in this way and followed up for up to 30 years have shown increased risk of cancer in another organ and heart disease that begins after 15 years.然而,治療的病人在這樣和跟進長達30年表明,增加患癌症的風險在另一器官和心髒病的開始, 15年後。

Tim Oliver (St Bartholomew’s and The London School of Medicine, London, UK) and colleagues recruited 1477 patients with stage 1 seminoma from 70 hospitals in 14 countries to compare radiotherapy with chemotherapy treatment.添奧利弗(聖巴托羅繆的和倫敦醫學院,倫敦,英國)和同事招募1477例第1階段精由70醫院在14個國家比較,放療與化療治療。 Between 1996 and 2001, the researchers randomly assigned 543 patients with stage I seminoma to receive a single course of carboplatin and 904 patients to receive radiation therapy. 1996至2001年間,研究人員隨機分配543例I期精接受一個單一的過程中卡鉑和904的病人接受放射治療。 After a median follow-up of 3 years, they found that relapse-free survival was similar between the two groups (95?4% for the carboplatin group vs 96?6% for radiation therapy).之後,中位數的後續行動,三年,他們發現復發無發展的存活是類似的兩個集團之間( 95 ? 4 % ,為卡鉑組與96呢? 6 % ,放射治療) 。 At 5 years they also found that patients receiving carboplatin were less likely to develop tumours in their remaining testicle.在五年他們還發現,病人接受卡鉑不太可能發展的腫瘤在其剩餘的睾丸。

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