Diabetes (Type 1) as you know is an auto-immune disease where our own cells attack the insulin generating islet cells, thereby progressively reducing the insulin generation capability of the body.糖尿病( 1型)正如你所知道是自身免疫病的地方,我们自己的细胞攻击产生胰岛素的胰岛细胞,从而逐步减少胰岛素一代的能力,身体。

The challenge with any treatment protocol which seeks to replace the destroyed cells is that the underlying auto-immune response has not been cured.挑战与任何治疗的议定书,旨在取代被破坏的细胞是基本的自动免疫反应并没有被治愈。 Edmonton protocol and other similar pancreas transplant or islet transplant protocols tries to address this by weakening the immune system of the body with plethora of drugs like Cyclosporine A, Cellcept etc. These drugs has serious side-effects including affecting the very organ they are intended to protect over long term, making the body vulnerable to myriad infections etc.埃德蒙顿议定书和其他类似的胰腺移植或胰岛移植议定书试图解决这一削弱免疫系统的机构,过多的药物一样,环孢素A , cellcept等,这些药物具有严重的副作用包括影响非常器官,他们打算保护超过长远,使身体容易受到各种感染等。

As you can easily infer from the above that the best solution to the problem would be to re-train the immune system not to attack the islet cells.正如您可以很容易地推断,从上述的表示,解决问题的最佳方法将是重新训练免疫系统不攻击胰岛细胞。 At that point it would simply be a matter of time till the islet cells regenerate from the remaining precursor cells or from donated cells.在这一点上,它只是一个时间问题,等到胰岛细胞的再生,从余下的前体细胞,或从捐赠的细胞。

And doctors have found out exactly that.和医生已经发现,正是这一点。

“We have found that it is possible to rapidly regrow islets from adult precursor cells, something that many thought could not be done,” says Denise Faustman, MD, PhD, director of the MGH Immunobiology Laboratory and principal investigator of the study. “我们已发现它是有可能的迅速再生,从成人胰岛前体细胞,这是许多人认为不能这样做,说: ”丹尼斯faustman ,医学博士,博士,主任的mgh immunobiology实验室和首席调查研究。 “By accomplishing effective, robust and durable islet regeneration, this discovery opens up an entirely new approach to diabetes treatment.” “完成有效的,强有力的和持久的胰岛再生,这一发现开辟了一个完全新的方法治疗糖尿病” 。

David M. Nathan, MD, director of the MGH Diabetes Center, notes, “These exciting findings in a mouse model of Type 1 diabetes suggest that patients who are developing this disease could be rescued from further destruction of their insulin-producing cells.朱米弥敦道,医学博士,主任的mgh糖尿病中心,笔记, “这些令人振奋的结果显示,在小鼠模型的1型糖尿病病人的建议谁是发展中国家的这种疾病可以获救,进一步破坏他们的胰岛素产生细胞。 In addition, patients with fully established diabetes possibly could have their diabetes reversed.”此外,病人与完全建立糖尿病可能有糖尿病,扭转“ 。

Nothing could be more exciting then this!没有什么能更激动人心的,然后这个!

Editors Note: The original news release can be found编者注:原新闻稿中可以找到 here这里 .